Nicholas Reyes
Lecturer, Senior Staff Veterinarian and Co-Director of Facilities and Operations
D.V.M., Western University of The Health Sciences 2011
M.S., University of Washington 2014
Diplomate, ACLAM 2016
P: 206-543-0267
E: nlreyes@uw.edu
Research, Service, and Training Interests
Dr. Reyes is the Co-Director of Animal Facility Operations and Chief of Veterinary Services in the Department of Comparative Medicine (DCM). In these roles he oversees staffing, equipment management and facility operations in the Department’s seven large vivarium spaces across multiple campuses. He also leads Comparative Medicine’s team of veterinary technicians and residents in the clinical care of all animals housed at the University of Washington for research purposes. Dr. Reyes is also an Assistant Teaching Professor in the DCM and an instructor in the resident training program wherein he coordinates and leads the large animal anesthesia resident rotation. In this rotation, he teaches trainees techniques and novel approaches to administering anesthesia and analgesia in laboratory animal species. In 2014, Dr. Reyes completed his residency in laboratory animal medicine at the University of Washington and soon after became a boarded Diplomate in the American College of Laboratory Animal Medicine (ACLAM). During his time in that program, he earned a Master’s Degree in Comparative Medicine. His research worked to characterize phenotypic changes observed in the skeletal muscle of mice deficient in Folliculin Interacting Protein-1 (FNIP1). Further investigation into the consequences of this imbalance helped to elucidate the significant role Fnip1 plays in regulation of skeletal muscle fiber determination and metabolic programming within a myofiber and revealed potential implications in the future treatment of muscular dystrophy. His current research interests include novel anesthetic protocols utilizing total intravenous anesthesia and the effects of different anesthetic strategies on tissue metabolism.
Selected Publications
Perinatal Psychoneuroimmunology of Prenatal Stress and Its Effects on Fetal and Postnatal Brain Development. Frasch, MG., Wakefield, C., Jeanoschek, B., Frand, YW., Karp, F, Reyes, N, Desrochers, A., Wallingford, MC., Antonelli, MC., and G.A.S. Metz. Chapter Psychoneuroimmunology, Methods in Molecular Biology. Online November 16, 2024, pp 303-332.
Alfaxalone as a Total Intravenous Anesthesia Protocol in New Zealand White Rabbits (Oryctolagus cuniculus) Improves Cardiovascular Stability Compared to Isoflurane. Tsai J, Palomera E, Kondo J, Jampachaisri K, Pacharinsak C, and Reyes NL. ACLAM Forum Presentation May 2024
Acute, Progressive Rear Limb Paresis in a Long Evans Rat N. Reyes, P. Treuting, P. Vogel, J. Rehg, J. Snyder. Journal of the American Veterinary Medical Association: Pathology in Practice. Aug 2016.
Fnip1 regulates skeletal muscle fiber type specification, fatigue resistance, and susceptibility to muscular dystrophy N. Reyes; G. Banks; M. Tsang; D. Margineantu; H. Gu; D. Djukovic; J Chan, M Torres, H. D. Liggitt; D. K. Hirenallur-S, D. M. Hockenbery; D. Raftery and B. Iritani. Proceedings of the National Academy of Sciences. Dec 2014
The Role of Fnip1 in Skeletal Muscle Metabolism, Fiber Type Specification, and Muscular Dystrophy N. Reyes, G. Banks, J. Ramírez, D. Hirenallur-S, M. Tsang, D. Margineantu, D. M. Hockenbery, H. Denny Liggitt, and B. M. Iritani. Trainee Research Platform Presentation. American Association for Laboratory Animal Science Annual Meeting. Oct 2014
Fnip1 Regulates Skeletal Muscle Fiber Type Specification, Fatigue Resistance, and Susceptibility to Muscular Dystrophy N. Reyes. Master’s Thesis. UW Department of Comparative Medicine. June 2014