Department of Comparative Medicine

Jenna Klug

Assistant Professor

D.V.M., Kansas State University, 2016

M.S, Comparative Medicine, University of Washington, 2019

Diplomat, ACVP (Anatomic), 2022

P: 206-616-1510

E: jklug13@uw.edu

About Dr. Klug

Dr. Klug received her Bachelor’s of Science in Biology and Minor in Political Science from Creighton University in Omaha, Nebraska in 2012, followed by a Doctorate in Veterinary Medicine (DVM) from Kansas State University College of Veterinary Medicine in 2016. She completed a residency in Laboratory Animal Medicine and a Master’s of Science in Comparative Medicine within the Department of Comparative Medicine at the University of Washington in 2019. She continued as a postdoctoral scholar in the same department, with a focus on comparative pathology from 2019 through 2021, and joined the DCM faculty as an acting instructor in 2021. She became board certified in anatomic pathology by the American College of Veterinary Pathologists in September 2022, and has served as an Assistant Professor since 2023.

Dr. Klug’s field of study is comparative pathology. Her specific areas of interest include rodent, small animal, NHP and cricket models of aging, as well as aquatic animal diagnostic pathology and models of disease. She serves as a duty veterinary pathologist on clinical service through the UW Veterinary Diagnostic Lab (UW VDL), as well as performs collaborative research and pathology consultations through the Comparative Pathology Program (CPP). Dr. Klug’s teaching responsibilities include leading pathology rounds for laboratory animal trainees and comparative pathology conferences, and serving as an instructor for DCM pathology courses and rotations, as well as Lab Managed Aquatics courses.

Dr. Klug is also involved with the Core: CPP (Comparative Pathology Program): https://www.uwcpp.com/home-6-2/cnp-p-2/

Selected Publications

  1. Sheehan S, Mawe S, Chen M, Klug J, Ladiges W, Korstanje R, Mahoney JM. (2024). A machine learning approach for quantifying age-related histological changes in the mouse kidney. GeroScience. 46(2):2571-81.
  2. Jiang Z, Wang J, Imai D, Snider T, Klug J, Mangalindan R, Morton J, Zhu L, Salmon AB, Wezeman J, Hu J, Menon V, Marka N, Neidernhofer L, Ladiges W. (2022). Short term treatment with a cocktail of rapamycin, acarbose and phenylbutyrate delays aging phenotypes in mice. Scientific Reports, 12(1):1-12.
  3. Klug J1, Christensen S, Imai DM, Snider TA, Ladiges W. (2021). The geropathology of organ-specific aging. Journal of Translational Science, 7(1): 458.
  4. Klug JJ1, Treuting PM, Sanders GE, Winton JR, Kurath G. (2021). Kinetics of Stocking Density on Stress Response and Susceptibility to Infectious Hematopoietic Necrosis Virus in Rainbow Trout. Journal of the American Association for Laboratory Animal Science, 60(6):673-45.
  5. Yousefzadeh MJ,  Flores RR, Zhu Y, Schmiechen ZC, Brooks RW, Trussoni CE, Cui Y, Angelini L, Lee KA, McGowan SJ, Burrack AL, Wang D, Dong Q, Lu A, Sano T, O’Kelly RD, McGuckian CA, Kato JI, Bank MP, Wade EA, Pillai SPS, Klug J, Ladiges WC, Burd CE, Lewis SE, LaRusso NF, Vo NV, Wang Y, Kelley EE, Huard J, Stromnes IM, Robbins PD, Niedernhofer LJ. (2021). An aged immune system drives senescence and aging of solid organs. Nature, 594(7861): 100-105.
  6. Klug J1, Snyder JM, Darvas M, Imai DM, Church M, Latimer C, Keene DC, Ladiges W. (2020). Aging pet cats develop neuropathology similar to human Alzheimer’s disease. Aging Pathobiology and Therapeutics, 2(3), 120-125.
  7. Klug J1, Davis DJ1, Hankins M, Doerr HM, Monticelli SR, Song A, Gillespie CH, Bryda EC. (2015). Effects of Clove Oil as a Euthanasia Agent on Blood Collection Efficiency and Serum Cortisol Levels in Danio Rerio. Journal of the American Association for Laboratory Animal Science, 54(5), 564-567. 1co-first authors

Selected Presentations

  1. Klug, J. (2018). Zebrafish Refinements. Oral presentation and refinement panelist at the Northwest Association for Biomedical Research (NWABR) Institutional Animal Care and Use Committee Conference, Lynnwood, Washington.
  2. Klug J. (2017). The Care and Use of Trout in Research. Oral presentation at the Washington Branch American Association for Laboratory Animal Science (AALAS) Trade Fair, Seattle, Washington.